Tear Film Osmolarity Measurement in Japanese Dry Eye Patients Using a Handheld Osmolarity System

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Variability of Tear Osmolarity in Patients With Dry Eye.

IMPORTANCE Knowledge about the variability of measurements using the TearLab Osmolarity System is necessary when evaluating the clinical utility of readings. OBJECTIVE To examine the variability of tear osmolarity measured by the TearLab Osmolarity System in patients with Sjögren syndrome (SS), patients with blepharitis, and control participants. DESIGN, SETTING, AND PARTICIPANTS Cross-sect...

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Tear osmolarity and dry eye symptoms in diabetics

PURPOSE To assess the relationship between tear osmolarity and dry eye symptoms in patients with diabetes. PATIENTS AND METHODS Fifty patients with diabetes were enrolled. Demographic information and past medical history were recorded. Symptoms were assessed using the ocular surface disease index (OSDI). Tear osmolarity of each eye was measured with the TearLab® Osmolarity System. RESULTS T...

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Tear osmolarity as a biomarker for dry eye disease severity.

PURPOSE To study the association between tear osmolarity and dry eye severity grade, based on a modified Dry Eye Workshop (DEWS) scale, and between osmolarity and the signs and symptoms that determine dry eye disease severity. METHODS Nineteen patients with dry eye disease were asked to complete an evaluation of dry eye signs and symptoms composed of the Ocular Surface Disease Index (OSDI) qu...

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Tear film osmolarity and dry eye disease: a review of the literature

OBJECTIVE To evaluate the evidence in the peer-reviewed literature regarding the use of tear osmolarity as a physiological marker to diagnose, grade severity, and track therapeutic response in dry eye disease (DED). In addition, to review the evidence for the role of tear osmolarity in the pathophysiology of DED and ocular surface disease. METHODS A literature review of all publications after...

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Tear film osmolarity: determination of a referent for dry eye diagnosis.

PURPOSE To determine new referents, or cutoff levels for tear film hyperosmolarity in the diagnosis of keratoconjunctivitis sicca (KCS) and to assess their effectiveness in independent patient groups. METHOD A meta-analysis was performed on published data for tear osmolarity in samples of normal eyes and various subtypes of dry eye, and pooled estimates of the mean and standard deviations for...

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ژورنال

عنوان ژورنال: Diagnostics

سال: 2020

ISSN: 2075-4418

DOI: 10.3390/diagnostics10100789